Mechanical performance of sutures exposed to natural extract-based mouthwashes.

Mechanical performance of sutures exposed to natural extract-based mouthwashes. scientific illustration

The Secret to Stronger Post-Surgery Healing May Be Hiding in Your Medicine Cabinet

If you’ve ever had oral surgery — wisdom teeth removal, gum treatment, or dental implants — you know the anxiety that comes with those dissolving stitches. Will they hold? Will they break down too quickly? What you rinse with afterward might matter more than you think, and new research suggests that natural mouthwashes could be the game-changer your recovery needs.

Natural mouthwashes containing propolis and licorice root extract may help maintain suture strength better than traditional options, with the combination of both ingredients showing the strongest protective effects on surgical stitches used in oral procedures.

What the Research Discovered

A groundbreaking study from King Saud University examined how different mouthwashes affect the strength of surgical sutures — those dissolvable stitches that hold your mouth together after procedures. The researchers tested two types of commonly used absorbable sutures against five different solutions, including artificial saliva, chlorhexidine (the gold standard antiseptic), and three natural herbal mouthwashes.

The results were striking: sutures exposed to natural herbal solutions maintained significantly higher tensile strength compared to those in artificial saliva. Most impressive was the combination of dipotassium glycyrrhizinate (from licorice root) and propolis extract, which consistently produced the highest suture strength across all testing periods.

Study Details:

Aspect Details
Publication Scientific Reports, 2026
Sample Size Multiple suture samples (PGA and PGCL types, sizes 3/0 and 4/0)
Duration 24 hours, 3 days, 1 week, and 2 weeks
Primary Outcome Tensile strength maintenance of surgical sutures
Key Finding Combined propolis-licorice extract showed highest suture strength preservation

The study found that suture type and the solution they were exposed to made statistically significant differences in strength retention, while the duration of exposure (surprisingly) didn’t show significant impact. This suggests that the protective benefits of natural extracts begin working immediately and maintain their effectiveness over time.

How This Applies to Your Daily Life

Understanding these findings could transform your post-surgical recovery experience. Here’s what this research means for anyone facing oral surgery:

  1. Your Mouthwash Choice Actually Matters for Healing

Research suggests that switching from standard rinses to propolis-based mouthwashes may support better suture integrity during the critical healing period. This isn’t just about keeping your mouth clean — it’s about giving your stitches the best environment to do their job. The mechanical support provided by stronger sutures could mean more predictable healing and potentially fewer complications.

  1. Natural Doesn’t Mean Weaker — It May Mean Stronger

While many people assume pharmaceutical options are always superior, this study indicates that natural extract-based mouthwashes may actually provide better mechanical support for healing tissues. The propolis and licorice combination outperformed traditional chlorhexidine in maintaining suture strength, challenging the assumption that “natural” equals “less effective.”

  1. Timing Your Post-Surgery Routine Could Be Crucial

Since the protective effects appeared consistent across all time periods tested, starting your natural mouthwash routine immediately after surgery (when cleared by your dentist) may provide optimal benefits. The research suggests these natural extracts don’t need time to “build up” — they start supporting suture strength from day one.

  1. Consider This Before Your Next Procedure

If you have upcoming oral surgery, discussing propolis-based post-operative care with your dental professional could be worthwhile. While you should never change your prescribed aftercare routine without approval, this research provides evidence-based talking points about potentially beneficial natural alternatives that may complement traditional healing protocols.

Mechanical performance of sutures exposed to natural extract-based mouthwashes. mechanism illustration

What You Should Know Before Using Propolis

While this research shows promising results for propolis in oral care, it’s essential to understand the practical considerations before incorporating it into your post-surgical routine.

Dosage and Application: The study used propolis extract in mouthwash form, though specific concentrations weren’t detailed in the available abstract. Most commercial propolis mouthwashes contain 1-3% propolis extract. For post-surgical use, follow your dentist’s instructions first, then consider propolis options as approved supplements to your care routine.

Safety Profile: Propolis is generally well-tolerated by most people, but some individuals may experience allergic reactions, particularly those with bee product allergies. Studies indicate that propolis allergies occur in approximately 1-3% of the population, often manifesting as contact dermatitis or oral irritation.

Who Should Avoid Propolis:

  • People with known bee product allergies
  • Those with asthma (propolis may trigger respiratory symptoms in sensitive individuals)
  • Pregnant or nursing women (limited safety data available)
  • Children under 12 (unless specifically recommended by a healthcare provider)
  • Anyone taking blood-thinning medications (propolis may enhance anticoagulant effects)

Always consult with your oral surgeon or dentist before adding any new products to your post-operative care routine, especially if you’re taking medications or have underlying health conditions.

Frequently Asked Questions

Q: Can I use propolis mouthwash immediately after oral surgery?
Never start any new oral care product immediately after surgery without your surgeon’s approval. Most post-surgical protocols require specific rinses or no rinsing at all for the first 24-48 hours. Once you’re cleared for gentle rinsing, propolis-based mouthwashes may be a beneficial addition, but timing and method should always follow your healthcare provider’s instructions. The research suggests benefits occur quickly once started, so you won’t miss out by waiting for proper clearance.

Q: Is propolis mouthwash better than prescription chlorhexidine rinses?
This study suggests that propolis may offer superior suture strength maintenance compared to chlorhexidine, but that’s just one aspect of post-surgical care. Chlorhexidine remains the gold standard for antimicrobial action and infection prevention. Rather than replacement, consider propolis as a complementary approach — some patients use chlorhexidine for infection control and propolis for healing support, though this should be discussed with your dental team first.

Q: What makes the propolis-licorice combination more effective than propolis alone?
The research shows that dipotassium glycyrrhizinate (from licorice root) combined with propolis produced the strongest suture preservation effects. Licorice root contains compounds that may enhance the mechanical properties of materials it contacts, while propolis contributes its own tissue-supporting properties. This synergistic effect suggests that combination products might offer superior benefits, though more research is needed to understand the exact mechanisms involved.

Q: How long should I use natural mouthwashes after oral surgery?
The study tested effects up to two weeks, which aligns with typical suture dissolution timeframes for most oral procedures. Since the research showed consistent benefits throughout this period, using propolis-based mouthwashes for the entire healing period (usually 2-4 weeks) may provide optimal support. However, your specific healing timeline depends on the procedure complexity, your health status, and your surgeon’s recommendations.

Q: Are there any side effects I should watch for with propolis mouthwashes?
Most people tolerate propolis well, but watch for signs of allergic reactions including mouth irritation, swelling, unusual taste changes, or difficulty swallowing. Some individuals report temporary staining of teeth or dental work with prolonged use. If you experience any unusual symptoms, discontinue use and contact your healthcare provider. Starting with shorter exposure times can help identify sensitivity before committing to regular use.

Natural health lifestyle

The Bottom Line

This research suggests that the mouthwash you choose after oral surgery could significantly impact how well your sutures perform during the critical healing period. While artificial saliva showed the lowest suture strength maintenance, natural extract-based mouthwashes — particularly the combination of propolis and licorice root extract — demonstrated superior protective effects. The findings indicate that natural doesn’t necessarily mean less effective; in fact, it may mean the opposite when it comes to supporting your body’s healing mechanisms. However, any changes to post-surgical care should always be discussed with your dental team first, as individual healing needs vary and professional guidance ensures the safest, most effective recovery possible.


Medical Disclaimer: This information is for educational purposes only and is not medical advice. Always consult a qualified healthcare professional. These statements have not been evaluated by the FDA.
Source: PubMed ID 41651921 | DOI: 10.1038/s41598-026-37932-x | Sci Rep
Authors: Alaqeely R, AlQahtani N, Alrobaish S, Hamdan H, Alduraihem H, Alrowis R, Alhotan A

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